The poly(aryl ether ketone) containing trifluoromethyl in the main chain (m-F-PAEK) and side chain (s-F-PAEK) were respectively synthesized through nucleophilic polycondensation. The structures of the two poly(aryl ether ketone)s were determined by 1H-NMR. DSC studies showed that Tg of the m-F-PAEK was 166oC, and that of the s-F-PAEK was 139oC. The higher Tg of m-F-PAEK was due to the trifluoromethyl in the main chain which had increased the rigidity. Moreover, the 5% thermal weightless temperature of the two polymers was above 490oC, indicating their good thermal stability. Water contact angle results showed that the water contact angle of the m-F-PAEK and the s-F-PAEK was 91o and 113o, respectively. The result demonstrated that s-F-PAEK had better hydrophobic performance than m-F-PAEK. This was because that the fluorine atoms of the s-F-PAEK more likely to migrate to the surface of the film after high temperature treatment, which decreased the surface energy further.

As a typical pH sensitive polymer with biocompatibility, hydroxypropyl methylcellulose acetate succinate (HPMCAS) is a promising material for application in controlled drug release. In this paper, HPMCAS micro-nanofibers were prepared through electrospinning. The optimum condition was obtained by researching the effective of the parameters such as solution concentration, applied voltage, distance and ratio of mixed solvent on fiber morphology and diameter. Through an orthogonal and a single factor experiment, the optimum parameters were determined as a polymer concentration of 12 wt %, a voltage of 20 kV, a collector distance of 20 cm and a solvent ratio (CH3OH/DCM) of 4/6. As a result, the average diameter of fibers is 363m and with good uniformity and smooth morphology. The results will provide theoretical and experimental basis for using HPMCAS nanofibers as intelligent ph-controlled drug sustained-release/controlled-release materials.

A novel platform based on reduced graphene oxide and SiO₂/CMC hybrid membranes(GO-SiO₂-CMC) was successfully constructed for the fabrication of biosensor. The morphologies and electrochemistry of the nanocomposite film were investigated by using scanning electron microscopy and electrochemical techniques including electrochemical impedance spectroscopy and cyclic voltammetry (CV), respectively. The results suggested that the modified electrode showed enhanced sensitivity towards the oxidation of Vitamin B6 (VB6), e.g., high detection sensitivity (31.5μAmM-1cm-2), a low limit of detection (10-7M), a small Ret value (252Ω) and a good stability. This might be attributed to large surface-to-volume ratio and high conductivity of graphene, which could promote direct electron transfer between the surface of electrodes and Vitamin B6 (VB6). These above results offered a simple, sensitive and flexible method for quantitative detection of Vitamin B6 through the technology of electrochemical.

With the development of social economy, water environment capacity has become one key factor that constrains the development of social economy and ecological environment. At present, chemical oxygen demand (COD) and ammonia nitrogen are the main pollutants in the main stream of Songhua River in Jilin City. In this paper, the one-dimensional steady-state model of river was adopted to calculate the water environmental capacity of COD and ammonia nitrogen in the main stream of Songhua River in Jilin city with the method of segment head control. The results showed that the water environmental capacity of COD and ammonia nitrogen in the main stream of Songhua River were 494513.5t/a and 24725.7t/a respectively, the current discharge were 265071.9t/a and 7347.2t/a respectively.  The remaining water environmental capacity of COD and ammonia nitrogen were 229441.6t/a and 17378.4t/a, respectively. At present, the water environmental capacity of COD and ammonia nitrogen in the main stream of Songhua River in Jilin City have a large surplus, which would provide a solid guarantee for the economic development of Jilin City.

A strain that degrades petroleum hydrocarbon was screened and isolated from oil-contaminated soil of Songyuan oilfield, its colony morphology was observed, and it was identified by 16S rDNA sequence analysis. The results indicated that the colony was white and irregular with rough surface and irregular edge. The 16S rDNA sequence was identified as Pseudomonas pseudoalcaligenes strain. When the temperature was 35℃ and the pH value was 8, the strain had the best degradation effect on petroleum hydrocarbon, and the degradation rate was 75.4%.

On the basis of collecting relevant safety laws, regulations and standards of pharmaceutical industry and technical data of pharmaceutical projects, this paper identifies and analyses dangerous and harmful factors from aspects of materials, production process and safety management, and puts forward corresponding safety facility design to effectively reduce the possibility of accidents, which has certain significance for the construction, reconstruction and expansion of pharmaceutical projects reference significance.

Ultrasonic-assisted extraction of total phenolic acid from Sedum aizoon L. was carried out. The extraction rate was determined by spectrophotometer. The effects of extraction time, temperature, ratio of material to liquid and concentration of ethanol on the extraction rate were discussed. On the basis of single factor extraction, orthogonal method was used to optimize the experiments. The results showed that the order of affecting the extraction rate of total phenolic acid was extraction temperature, followed by extraction time, ratio of material to liquid, ethanol concentration. The optimum extraction conditions were: extraction temperature 60℃, extraction time 60 min, ratio of material to liquid 1:8, ethanol concentration 70%, and the total phenolic acid of Sedum aizoon L. was 3.62%. The antioxidant capacity of total phenolic acid of Sedum aizoon L. is similar to Vc, which indicates that Sedum aizoon L. has good antioxidant capacity.

Objective: Establishing a mouse femur bone defection model. Methods: Three 8-week-old female C57BL /6J mouse were used in this experiment. A hole with 1mm diameter was drilled on the distal femur. Then, the sulfonated polyetheretherketone(PEEK) with 1 mm diameter and 5 mm length was implanted into the femur marrow cavity. Micro-CT was used to reconstruct the bone microstructure and observe the implant position. Results: The health condition of mice with bone defection is good post-surgery and can survive until sacrifice. The movement of them is unlimited. The photos show that the implantation is fine placed in the femur marrow cavity. There is not any obvious damage. 3D reconstructed micro-CT images show that the position of implantation is fine. Conclusion: The mouse femur defection model was successfully established in this work.

Rural domestic sewage treatment in northern of China is seriously affected by low temperature. In order to solve this problem, the activated sludge with good treatment effect on sewage at 8℃ was obtained by low temperature domestication, and its sewage treatment effect was analyzed. The results showed that when the domesticated sludge with dry weight concentration of 3.4g?L-1 was used to treat rural domestic sewage, the highest COD removal rate of the rural domestic sewage was 84.97%, the lowest COD of the effluent was 89.51 mg?L-1, and the shortest treatment time of reaching irrigation water quality standard of farmland (GB 5084-2005) was 8 days. Compared with the non-domesticated sludge, the COD removal rate of sewage after the activated sludge acclimated increased by 23.14%, which provided good technical support for rural domestic sewage treatment in northern of China.

In order to study the influence of channel size on the performance of proton exchange membrane fuel cell (FEMFC), A three-dimensional model of proton exchange membrane fuel cell was established by COMSOL. The influence on fuel cell performance was analyzed when the ratio of channel width to ridge width is 1:1, 1:2 and 1:3, respectively, and the validity and reliability of the model was verified. Further study shows that when the ridge width remains unchanged, the ratio of the channel width to the ridge width is 1:1, 2:1, and 3:1, respectively. The influences of current density, hydrogen concentration at anode and oxygen concentration at cathode were analyzed. It is found that which is the best size ratio of fuel cell of channel width to ridge width is 1:1, and the ridge width has more influence on the fuel cell performance than the channel width.

Using single chip microcomputer as main control device to control the quality of the gas flow and shows that the shell of the machine adopts the material of 316 l stainless steel temperature sensor consisting of thermal type gas mass flowmeter and automatic control of the transmitter, flow through acquisition, A/D conversion and control of the CPU, and through digital tube display and so on A series of hardware and software functions of the auxiliary implementation, complete control of the flow measurement.

Aiming at trash cans in public places such as districts, schools, streets, and stations, a new type of turnover trash was developed, which integrated the efficient garbage cleaning, battery recycling and public service billboards. Dump the garage into the garbage track through raising the handle and the L-shaped bracket. It only takes 2 seconds to turn the trash to a specified height, when a 200N force applied to the handle. It is convenient and quick. Based on the rigid-flexible coupling model of the turnover trash, the dynamic stress during the working process of the trash, L-shaped bracket, and handle is analyzed. The maximum dynamic stress is 147.51KPa, 119.37KPa, and 75.21KPa. The stress of trash at the moving end is greater than the stress at the active end, and both are less than the material's yield strength of 170 MPa, which provides a basis for related design.

Based on fdm3d printing technology, this paper designs a five in one out printing head for color 3D printing by using the principle of magenta yellow blue primary color matching. For 3D printing of melt deposition, the unreasonable thermal structure and distribution of the print head in the printing process will affect the accuracy of the whole printing process and the quality of the print. The thermal analysis method is used to optimize the structure of the five in one out printing head. The temperature distribution of the five in one out printing head in the printing process can be observed more intuitively. The rationality of the structure of the five in one out printing head is verified, which provides technical theoretical support for color 3D printing based on FDM.

In order to improve the rehabilitation efficiency of cerebral thrombosis patients and reduce the intensity of nursing, a rehabilitation training robot for cerebral thrombosis patients was designed. The rehabilitation training robot can assist patients to switch between standing posture and sitting posture. In sitting posture, the rehabilitation training robot can realize the function of electric wheelchair. In standing posture, it can assist patients to walk through exoskeleton.

Using the quaternions to solve attitude transformation matrix, using the three-axis rotation composite into the attitude angle transformation matrix, complete the software design of the algorithm based on the scale transformation in attitude measurement, through the measurement sensor MPU6050 circuit design and programming experiments, and the establishment of the upper machine 3D model, to verify that the method can work full-position, real-time, moderate calculation the measurement results meet the needs of the level measurement application.

Analyze and set up the dynamic mathematical model of tube and shell heat exchanger to difference instead of differential model of the digital based on material balance and energy conservation, through configuration chopped control software scripting language to compile the dynamic real-time simulation program of tube and shell heat exchanger and to simulate the heat transfer in the process of each process parameter change of heat-exchange terminal temperature influence, for heat exchange field engineering of the actual working process of the research of control circuit and parameters adjustment has certain guidance and reference significance.

In this paper, the data set for human activity recognition collected by the wearable device is processed, and the processed data is used to train a one-dimensional convolutional neural network to test and obtain accuracy results. The processing of the data set allows some noise and invalid data in the original data set to be filtered out, which reduces the amount of calculation and improves the efficiency of the neural network when training the neural network. After testing, under the condition that the structure of the neural network is unchanged, the processed data set can improve the performance of the neural network.

In the process of coal mining, hydraulic support is used as a supporting equipment for coal mining, and its strength performance determines the safety index of coal mining. Previous studies have shown that the stress of hydraulic support mainly concentrates on the column nest, and the magnitude of stress is related to the structure of the column, under this premise, the column structure of QY200 hydraulic support is optimized. On the premise of not changing the diameter of the column socket, the structural size of the column is optimized. The orthogonal test design method is adopted to optimize the test, and the overall stress of the hydraulic support is near the minimum as the optimization objective. The optimization results show that the maximum equivalent stress of hydraulic support increases with the increase of the length of live column. In order to ensure that the hydraulic support can work stably, the smaller of the column length is, the larger the outer diameter and the length of the cylinder will be.  The optimization method could reduce the number of tests and improve the design efficiency.

Wireless sensors can be integrated with energy collection devices for Long-term Autonomous Battery Energy Management. The existing research is based on the state of the battery is fully known, but accurate estimation of this information is difficult to achieve. In this paper, a performance index function is defined to compare the advantages and disadvantages of different transmission strategies. Considering the process of energy collection, the specific method of energy independent reaching optimization is analyzed. Combining the information of energy transmission channel gain, the corresponding transmission strategies are designed for different scenarios. Based on the analysis of the performance index and simulation of the strategy, the optimal transmission strategy of the Wireless sensor network is obtained.

Value at risk was introduced for the first time in railway freight safety. Based on the critical value idea of Value at Risk, combined with the Value at Risk model of dangerous goods transportation, this paper proposes a Value at Risk model suitable for the safe operation of railway freight.