Cultivating high-quality technical and skilled personnel is an important task in the development of education in China, and practice has shown that school-enterprise cooperation is an important means to achieve the goal of cultivating educational talents. This paper mainly studies how to build an effective institutional system for school-enterprise cooperation in accounting majors. After researching the survey data, the advantages and existing problems of the accounting profession are found, and the solutions to the problems are proposed through school-enterprise cooperation.