Application-oriented undergraduate colleges shoulder the important responsibility of training engineering talents. At present, there is still a shortage of talents in computer science and technology. Therefore, it is imperative to explore a new model of professional practice teaching with innovation and entrepreneurship as the target of talent training. To explore strengthening practical training from the perspective of service innovation and entrepreneurship, the specific content includes two aspects. On the one hand, to mobilize the students' self-entrepreneurship consciousness and implement the cultivation of innovation and entrepreneurship quality in combination with industry-university cooperation engineering projects; The second aspect is to combine the construction of new engineering and rely on discipline competition to improve the practical curriculum system and enhance students' innovative consciousness.