Physical Chemistry Experiment is a compulsory and basic course for science and engineering majors of higher education, which plays a vital role in cultivating the students' innovative thinking, practical ability and application ability. Under the background of engineering education accreditation, the thoughts are proposed by the teaching team of Physical Chemistry Experiment course of Jilin Institute of Chemical Technology in terms of the revision of course curriculum, the construction of online courses, the construction of a multi-level experimental system, and the integration of ideological and political elements in the course.