Based on the construction of the experimental center of the College of Resource and Environmental Engineering of Jilin Institute of Chemical Technology, this articl discusses the establishment of the experimental center, management mechanism and construction measures, and achievements, and establishes a set of effective operation mechanism and management mode of the experimental center. The establishment of the experimental center provides a strong support for the "engineering education professional certification" and "double first-class" undergraduate, simultaneously creates the good material condition for the teachers and students to carry out the scientific research activity and the specialized practice teaching.