Rooting in industry and serving local areas is the way of survival for the local application-oriented undergraduate colleges and universities. Adhering to the road of combining production, teaching and research is the key to the development of the colleges and universities. Taking Jilin Institute of Chemical Technology as an example, this paper explores the rich practice of combining production, teaching and research from the aspects of meticulous planning of top-level design of school development, training of talents' characteristics and social services, and provides a vivid case for the development of the local application-oriented undergraduate colleges and universities.