With the increase of the talents demanded by society, the training of students in colleges tends to be comprehensive and quality-oriented. Therefore, the reform of teaching mode in colleges emerges in endlessly. The core purpose of the reform is to improve the efficiency of classroom teaching. With this purpose, the "flipped classroom" teaching mode has been gradually used by educators in classroom teaching. The "flipped classroom" is a teaching mode marked by the return of students' learning subject status. Based on the characteristics and teaching status of the course "Fundamentals of Material Analysis", this paper elaborates on the application of the "flipped classroom" teaching mode in the teaching of the course, which fully reflects the application value and significance of the "flipped classroom" teaching mode. Its purpose is to improve the teaching quality and efficiency of the specialized course of material science, so as to cultivate practical materials science and engineering professionals to meet the needs of society.