According to the standard of reuse water, the effluent after secondary treatment of oil refining production is advanced treated. The reasonable technical design and process operation parameters are determined by experimental research, so that the effluent after advanced treatment can meet the requirements of circulating cooling water quality. re used in the production plant system to reuse the supplementary water of circulating water, which can not only save water resources, reduce production costs, but also reduce the serious pollution of the water body of the natural environment caused by the discharge of sewage, so as to achievewin of economic and environmental benefits.