In order to cultivate talents for different safety management positions, some enterprises of different industries are surveyed. The enterprises' specific requirements of the quality, ability and knowledge of safety management talents are taken as a guide, and the professional direction characteristics of occupational safety, engineering safety and public safety are combined. From the three aspects of comprehensive education, professional education, general education, we establish a training model for safety management talents, and construct the teaching contents and framework of knowledge system. Then the direction of teaching reform has been put forward. It provides effective suggestions for further improving the training mode of safety management talents.