The ideological and political education is an important measure to improve the quality of personnel training. Under the background of the booming development of cross-border e-commerce, teachers in charge of teaching of cross-border e-commerce should conduct in-depth research on the integration path of cross-border e-commerce teaching and the ideological and political education of the course. While teaching professional knowledge, teachers should organize ideological and political elements in cross-border e-commerce courses, integrate them into all aspects of classroom teaching, and play the role of building a soul through the main classroom channel, imperceptibly promote students to receive value guidance to achieve the ultimate goal of building morality and cultivating people.