The extraction technology of proanthocyanidin from Crataegus pinnatifida Bunge by ultrasonic assisted methanol was investigated in this paper. Four different factors: extraction temperature, extraction time, solvent concentration, solid-liquid ratio were selected in Orthogonal experiment. The most optimal conditions were confirmed as concentration 70%, extraction temperature 60℃, solid-liquid ratio 1:15, extraction time 30 min, and the extraction yield of proanthccyanidins from Crataegus pinnatifida Bunge reached to 1.781%.