Based on the analysis of the present situation of entrepreneurship education in application-oriented undergraduate universities, the problems like the imperfect construction of innovation entrepreneurship education curriculum system in the application-oriented undergraduate colleges and universities, the weak faculty, the hard integration of innovative entrepreneurship education into the campus culture are presented. Therefore, it is proposed that application-oriented undergraduate universities should take the opportunity of establishing the curriculum system and evaluation system of innovation and entrepreneurship education to explore the development path of innovation and entrepreneurship education integrating industry characteristics and improve the system of new entrepreneurship education.