In order to have a more comprehensive understanding of the research status and trends in the field of chemical safety, this paper takes "Chemical Safety" as the theme and explores the research status, hot issues and trends in the field of chemical safety with the help of visual tool CiteSpace. The results of the research show that: in recent years, the hot issues of the research in chemical safety field is increasing year by year. The cooperation between scholars and institutions is not close enough. The research focus of chemical safety varies in different stages, and technology management is one of the future research trends.