In order to make the training of safety professionals meet the needs of enterprises and better serve the economic development of local industries, it is necessary to explore the university enterprise collaborative education mode of safety professionals in local universities. Taking full account of the professional certification requirements of engineering education and the professional admittance system of certified safety engineers, four education modules are designed, including the reform of curriculum content and system, the construction of diversified practice bases, the construction of long-term teaching staff, and the design of innovation practice, the organic docking of enterprise and university diversified resources is realized. Make safety professionals become the power of enterprise safety production, and effectively promote the development of education resources to serve the regional leading characteristic industry.