In the era of big data, intelligent classroom emerges as a new classroom teaching mode with advanced teaching concepts, rich learning resources, three-dimensional learning evaluation methods and other characteristics. Based on the new concept of intelligent classroom, through the analysis of Chemical Economic and Management, this paper explores the construction of intelligent classroom of the course with the students' autonomous learning as the center to inspire the students' interest in learning, promote the students to acquire wisdom, cultivate the intelligent chemical management talents of ambition, literacy and responsibility.