By consulting relevant literatures, accident cases, and conducting research and exchanges with fraternal colleges, the paper analyzes the shortcomings of the laboratory fire fighting and emergency evacuation of universities: no emergency supplies, no use of fire extinguishers, unclear emergency responsibilities, no emergency plans, no emergency training, etc. The national standard "Guidelines for preparation and implementation of fire fighting and emergency evacuation plans for workplaces" (GB / T 38315-2019) has been implemented. In accordance with the requirements of the new standard and in combination with the preparation and implementation of the fire fighting and emergency evacuation plan of our college's laboratories, the key elements of the plan preparation procedures, main content, and implementation of the plan are exchanged and discussed, hoping to have a certain reference to the emergency management work of the relevant units.