Journal of Jilin Institute of Chemical Technology, 2019, 36(9): 10-13    doi: 10.16039/j.cnki.cn22-1249.2019.09.003
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Starch-based Microparticles of Polyoxometalate Antitumor Drug:Preparation and Characteristics
Qu Xiaoshu, Shi Dan, Zhang Li, Liu Yan
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Abstract  

A polyoxometalate antitumor drug delivery system, K14[NaP5W29O107]·40H2O starch-based microparticles (P5W29-CSM for short), have been prepared by the inverse emulsion method using soluble starch as raw material, epichlorohydrin as crosslinker. The preparation process of starch microspheres drug delivery was explored and determined. The structure of P5W29-CSM was characterized by SEM, IR, X-ray powder diffraction and UV-visible spectroscopy. The content of polyoxometalate in P5W29-CSM was 4.9% which is determined by UV spectrophotometry.

Key words polyoxometalate      antitumor      starch microparticles      preparation      
Published: 25 September 2019
:  O635.2  
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Qu Xiaoshu
Shi Dan
Zhang Li
Liu Yan
Cite this article:   
Qu Xiaoshu,Shi Dan,Zhang Li, et al. Starch-based Microparticles of Polyoxometalate Antitumor Drug:Preparation and Characteristics [J]. Journal of Jilin Institute of Chemical Technology, 2019, 36(9): 10-13.
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https://xuebao.jlict.edu.cn/EN/10.16039/j.cnki.cn22-1249.2019.09.003     OR     https://xuebao.jlict.edu.cn/EN/Y2019/V36/I9/10