Water quality engineering I is a core compulsory course of water supply and drainage science and engineering. At the same time, water quality engineering I course teaching and practice teaching are connected with each other, and there are certain hours of water quality engineering I course design, water quality engineering I related experiments and internships. Based on the characteristics of water quality engineering I course and the practical teaching content of water supply and drainage science and engineering related to the course, this paper discusses how to combine the practical teaching to improve the teaching effect of water quality engineering I course.