A tetra-substituted pyrimidine containing perfluoropropyl group (DMA-PM) was synthesized using the "one-pot multi-component" method, and two crystal materials (A and B) were cultured by solution volatilization. As a kind of mini fluorophore, the crystal material has obvious blue CIE (0.19, 0.12) and yellow CIE (0.49, 0.51) fluorescence, and their maximum emission wavelengths are 435 nm and 563 nm, respectively. Crystallographic studies have shown that this interesting emission phenomenon is rationalized to originate from the weak-interactions-dependent emission and conformation planarity in their crystal structures.