The establishment of morality and talents nurturing is the fundamental task of education, so it is of great significance to integrate the establishment of morality and talents nurturing into Organic Chemistry teaching, which is also the essential need of higher education in China. Taking "Organic Chemistry" as an example, the necessity of the task was deeply analyzed in this paper, and the measures were discussed for this issue from the aspects of the teacher's sense of responsibility, curriculum system, communication platform and assessment method.