The preparation technology, quality evaluation of total triterpenoid saponins hard capsule from Orostachys fimbriatus (Turcz) Berger were discussed in this paper. Taking the moisture absorption rate and the angle of repose as the indicators, the best excipients and amount of auxiliary materials were selected, and the bulk density was used to determine the capsule loading, determine the relative critical humidity of filling capsules by using moisture absorption rate as an indicator. In the process of quality inspection, the disintegration time and moisture content of hard capsules were examined.The preparation process conditions of the total triterpenoid saponins hard capsule from Orostachys fimbriatus (Turcz) Berger were optimized by experiments, which ensured the quality stability and reliability of the products and provided scientific theoretical basis for industrial production.
周明, 王亚红, 褚旭. 瓦松总三萜皂苷硬胶囊的制备及质量评价
[J]. 吉林化工学院学报, 2019, 36(1): 21-24.
ZHOU Ming, WANG Ya-hong, CHU Xu. Preparation and Quality Evaluation of Total Triterpenoid Saponins Hard Capsule from Orostachys fimbriatus (Turcz) Berger. Journal of Jilin Institute of Chemical Technology, 2019, 36(1): 21-24.