瓦松总三萜皂苷硬胶囊的制备及质量评价

doi:10.16039/j.cnki.cn22-1249.2019.01.005

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摘要

本文研究瓦松总三萜皂苷硬胶囊的制备工艺及质量评价。以吸湿率和休止角为考察指标，筛选出最佳辅料及辅料量，并用堆密度来确定胶囊装量，以吸湿率为考察指标确定装胶囊的相对临界湿度。在质量检查的过程中，对硬胶囊的崩解时限、水分含量进行检查。实验优化得到瓦松总三萜皂苷硬胶囊的制备工艺条件，对其质量进行了评价，确保了产品的质量稳定性与可靠性，为工业化生产提供了科学的理论依据。

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	周明
	王亚红
	褚旭

关键词: 瓦松总三萜皂苷硬胶囊质量研究

Abstract:

The preparation technology, quality evaluation of total triterpenoid saponins hard capsule from Orostachys fimbriatus (Turcz) Berger were discussed in this paper. Taking the moisture absorption rate and the angle of repose as the indicators, the best excipients and amount of auxiliary materials were selected, and the bulk density was used to determine the capsule loading, determine the relative critical humidity of filling capsules by using moisture absorption rate as an indicator. In the process of quality inspection, the disintegration time and moisture content of hard capsules were examined.The preparation process conditions of the total triterpenoid saponins hard capsule from Orostachys fimbriatus (Turcz) Berger were optimized by experiments, which ensured the quality stability and reliability of the products and provided scientific theoretical basis for industrial production.

Key words: orostachys fimbriatus (Turcz) berger total triterpenoid saponins hard capsule quality

出版日期: 2019-01-25 发布日期: 2019-01-25 整期出版日期: 2019-01-25

R932

引用本文:

周明, 王亚红, 褚旭. 瓦松总三萜皂苷硬胶囊的制备及质量评价 [J]. 吉林化工学院学报, 2019, 36(1): 21-24.
ZHOU Ming, WANG Ya-hong, CHU Xu. Preparation and Quality Evaluation of Total Triterpenoid Saponins Hard Capsule from Orostachys fimbriatus (Turcz) Berger. Journal of Jilin Institute of Chemical Technology, 2019, 36(1): 21-24.

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https://xuebao.jlict.edu.cn/CN/10.16039/j.cnki.cn22-1249.2019.01.005 或 https://xuebao.jlict.edu.cn/CN/Y2019/V36/I1/21

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