The great founding spirit of the Party is the source of the spirit of the Communist Party of China and integrating it into the ideological and political education of college students is conducive to the implementation of the fundamental task of moral cultivation in colleges and universities.This article systematically elaborates on the integration principles of unity of directionality and scientificity, unity of theory and practice,unity of dominance and subjectivity,and combination of explicit indoctrination and implicit infiltration,based on this,it proposes that in the new era,universities should consolidate the first classroom position,leverage socialpractice,build an online and offline model,and strengthen the construction of campus culture to build a path for integrating the great founding spirit of the Party into the ideological and political education of college students.